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KMID : 0360220210620040439
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Journal of the Korean Ophthalmological Society
2021 Volume.62 No. 4 p.439 ~ p.446
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Long-term Outcome of Combined Laser-assisted Subepithelial Keratomileusis and Accelerated Corneal Crosslinking for Myopia
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Yoon Yi-Sang
Kim Kook-Young
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Abstract
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Purpose: We compared clinical outcomes between combined laser-assisted subepithelial keratomileusis and accelerated collagencross-linking (Avedro-LASEK), and LASEK alone.
Methods: This retrospective study analyzed 38 eyes of 19 patients who had undergone Avedro-LASEK, and 34 eyes of 17 patientswho received LASEK alone. Uncorrected distance visual acuity (UDVA), spherical equivalent (SE), keratometry, and cornealinflammation were evaluated preoperatively, and at 1 week, 1, 3, and 6 months, and 1 and 2 years after surgery.
Results: The Avedro-LASEK group had a higher preoperative SE (p < 0.05) and thinner central cornea compared with the controlgroup (p < 0.05). There was no significant difference in UDVA, SE stability or keratometry between the two groups during the2-year follow-up period. At the 2-year follow-up, the SE was ± 0.25 diopter (D) in 92% of the Avedro-LASEK patients and ± 0.5D in 90.2% of the LASEK patients. Both groups showed high levels of refractive predictability. There was no significant differencebetween the flat K (p = 0.38) and steep K (p = 0.56) rates over time between the two groups.
Corneal haze was observed in 21%of eyes in the Avedro-LASEK group, but neither decreased vision nor ectasia was observed during the follow-up period.
Conclusions: During the 2-year follow-up period, there were no significant differences in any parameters between theAvedro-LASEK and LASEK patients, and both procedures are considered effective for myopia correction because of their stabilityand effectiveness.
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KEYWORD
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Corneal collagen crosslinking, Efficacy, Laser-assisted subepithelial keratomileusis, Myopia, Safety
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